Study -
Safety assessment of starch-based personal care products: Nanocapsules and pickering emulsions

The safety profile of the ingredients used in topical dosage forms and its evaluation is an issue of utmost importance. A suitable equilibrium between safety and efficacy is crucial before promoting a dermatological product. The aim of this work was to assess the safety and biological effects of starch-based vehicles (St-BV) used in such products. The hazard, exposure and dose-response assessment were used to characterize the risk of each ingredient. The EpiSkin™ assay and human repeat insult patch tests were performed to compare the theoretical safety assessment to in vitro and in vivo data. The efficacy of the St-BV was studied using biophysical measurements in human volunteers during 28 days, showing that all ingredients and their combinations were safe for the consumer. Tissue viability determined using the EpiSkin™ testing reached values between 84.0 ± 5.0% and 98.0 ± 8.6% after application of St-BV, which were considered as non-irritant to the skin. These observations were confirmed by the in vivo studies where the St-BV did not induce any sensitization on the volunteers, being safe for human use. Moreover, St-BV increased skin hydration and microcirculation, emerging as an attractive alternative to chemical raw materials...

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France -
Injonction de l'ANSM à la société Centiflor

C'est au nom de "non-conformités et de manquements importants" que l'ANSM vient d'envoyer à la société Centiflor (qui détient les marques Huiles & Sens et MaCosmetoPerso) une injonction de mise en conformité portant sur son établissement d'Entrechaux. En cause : plusieurs écarts relatifs au respect des exigences du Règlement Cosmétiques 1223/2009 et de la norme ISO 22716 relative aux Bonnes Pratiques de Fabrication. Cette injonction, en date du 16 février 2018, fait suite à une inspection de l'ANSM effectuée dans les locaux de cette société les 16 et 17 mai 2017...

Study -
Preparation, characterization, and antimicrobial activity of nanoemulsions incorporating citral essential oil

Citral is a typical essential oil used in the food, cosmetic, and drug industries and has shown antimicrobial activity against microorganisms. Citral is unstable and hydrophobic under normal storage conditions, so it can easily lose its bactericide activity. Nano-emulsion technology is an excellent way to hydrophilize, microencapsulate, and protect this compound. In our studies, we used a mixed surfactant to form citral-in-water nano-emulsions, and attempted to optimize the formula for preparing nanoemulsions. Citral-in- water nanoemulsions formed at S o 0.4 to 0.6 and ultrasonic power of 18...

France -
L’industrie des cosmétiques se tourne vers de nouvelles générations de lipides

En parallèle à l’ouverture de son bureau en Nouvelle Aquitaine, le pôle de compétitivité Cosmetic Valley a souhaité mettre en avant le savoir-faire de la région dans les lipides en co-organisant le 1er congrès Lipids & Cosmetics, les 25 et 26 janvier 2018 à Bordeaux. Durant deux journées, 150 participants ont assisté à des conférences sur l’innovation dans le domaine des lipides qui sont des matières stratégiques pour l’industrie cosmétique...

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