USA – Designing a Drug-Delivery Device? Read This First

In pharmaceutical industries, medicines are developed to treat certain illnesses. There are several types of delivery systems with which these medicines can be administered into the human or animal body. Injectable medicines are mainly administered with the help of syringes or delivery devices. Syringes or delivery devices are used with needles to inject the medicine or drug into the body.

However, a major challenge is to develop the syringe or delivery device which can be used to deliver the drug under the skin with more comfort and less pain. Injecting the drug under the skin with the help of syringes is mostly dependent upon the fluid properties of the drug. The design of delivery devices or syringes is based on fluid properties of the medicine or drug. It becomes more inconvenient or painful to the patient if the drug or fluid is with high viscosity or semi-solid type which needs high force to inject.

So, it is very important to understand the pressure and force requirement for delivery of highly viscous fluid. Based on the force requirement to deliver the drug, the device designer can design and develop a delivery system which would be used by the patient or user with more comfort and less pain. For the measurement of force, injectable drugs or fluids are classified as Newtonian and non-Newtonian fluids. The information in this paper on a mathematical equation, experiments, and suggestions will help the pharmaceutical industries as a basis to design and develop the syringes or drug delivery devices to deliver highly viscous, semi-solid or visco-elastic type of drug or medicine. The design parameters or functional features of the drug delivery device can be collectively called as design formulation. So, for a drug-device combination product, both the things viz. design and drug formulations are equally important for its safety and efficacy…