USA – Hairy Coating Keeps Nanoparticles Safe from Immune System, Liver

Nanoparticles are seemingly a great way to treat tumors, but they’re so rapidly washed out by the bloodstream that few of the nanoparticles actually reach their targets. Researchers at Drexel University have now developed a surface treatment that gives nanoparticles a significant advantage to overcome the body’s filtration system and therefore make nanotherapies much more effective.

The researchers developed hairy polymer shells within which nanoparticles can be encapsulated, and which the immune system ignores, while the liver lets the shells circulate back into the bloodstream.

Plasma proteins are a primary way for the body to tag which objects the immune system should get rid of, and macrophages then act to remove them…