China – Experimental Chinese COVID-19 vaccine is safe, according to researchers

An experimental COVID-19 vaccine currently being developed by the Institute of Medical Biology in China, under the Chinese Academy of Medical Sciences, appears to be safe, according to researchers.

The study, published on the pre-print server medRxiv, included results from a phase 1 trial of 191 healthy volunteers aged between 18-59 years old. In this trial, the vaccine did not induce any severe adverse reactions, according to researchers.

Among the most common adverse reactions were mild pain and fatigue as well as redness, itching and swelling at the injection site. In addition to the safety data, the study also identified that the experimental vaccine was able to induce an immune response against SARS-CoV-2, which causes COVID-19, in volunteers.

The activation of genes related to T cells, B cells, DCs and mononuclear cells/macrophages with varying dynamics is evidence of the immune response elicited by the vaccine,” the researchers noted…