Europe – SCCS : OPINION on Prostaglandins and prostaglandin-analogues used in cosmetic products

In light of the data provided, does the SCCS consider Isopropyl cloprostenate (CAS
157283-66-4) and Ethyl Tafluprostamide or DDDE (CAS 1185851-52-8) safe when
used up to the concentrations provided in the respective dossiers (0.006% and
0.007% for Isopropyl cloprostenate and 0.018% for Ethyl Tafluprostamide)
Having considered the limited data provided and the available information from
published literature, the SCCS is not able to conclude on the safety of isopropyl
cloprostenate and ethyl tafluprostamide when used up to the intended use
concentrations indicated in the respective dossiers (0.006% and 0.007% for
isopropyl cloprostenate and 0.018% for ethyl tafluprostamide)…