International – Study finds mixed vaccine schedules provide strong immune response against COVID-19

Mixing COVID-19 vaccines as part of a two-dose schedule generates a strong immune response against the SARS-CoV-2 virus, a study led by Oxford University suggests.

The Com-Cov study was initially launched in February, becoming the first trial in the world to evaluate whether different vaccines can be used safely and effectively as part of two-dose regimens.

The first results from the study suggest that two mixed schedules – a first dose of the Pfizer/BioNTech vaccine followed by the AstraZeneca/Oxford University vaccine or a first dose of the AstraZeneca/Oxford University vaccine followed by the Pfizer/BioNTech vaccine – provide good protection against COVID-19.

Specifically, these mixed vaccine schedules induced high concentrations of antibodies against the SARS-CoV-2 spike IgG protein when the doses were given four weeks apart…