The World Health Organization (WHO) issued a draft document Wednesday on environmental aspects of good manufacturing practices (GMP) to aid inspectors and manufacturers of antimicrobials.
The 24-page document is intended to raise awareness on interpreting relevant GMP guidance sections applicable to managing waste and wastewater from antimicrobials’ production, considering all GMP implementation aspects and focusing on critically important antimicrobials to establish and enforce requirements on safe waste and wastewater disposal. The draft also proposes ways to control and reduce the contamination of environments with antimicrobials and chemicals from production processes.
The move forms part of WHO’s response to the threat of antimicrobial resistance (AMR). WHO seeks input on the draft, including the proposals for ways to combat AMR when manufacturing drugs.
WHO explains AMR is a broader term than antibiotic resistance because AMR encompasses resistance to drug treatments of bacterial infections caused by more microbes such as parasites, whereas antibiotic resistance is limited to bacteria. But both have been spreading in recent years, posing a global crisis…