International – WHO updates COVID vaccine and clinical care guidelines

The World Health Organization (WHO) has released recommendations that include the use of low-dose anticoagulants for hospitalized patients with COVID-19 to reduce the risk of venous thromboembolism. That recommendation accompanies four other updates to the agency’s “living guidance” document for clinical management of patients with COVID-19.

For inpatients, the specific anticoagulation regimen recommended is thromboprophylaxis-level dosing rather than intermediate or therapeutic dosing for inpatients with COVID-19, barring indications for higher levels of anticoagulation medications.

For the subset of symptomatic COVID-19 patients at home who are at risk for progression to severe disease, the document recommends pulse oximetry monitoring “as part of a package of care” that includes education and follow-up…