UK – ICR calls for further discussions following NICE’s rejection of breast cancer drug

The Institute of Cancer Research (ICR) has called for further discussions between AstraZeneca (AZ), NHS England and the National Institute for Health and Care Excellence (NICE) following the decision not to recommend olaparib for women with early-stage, high-risk, inherited breast cancer.

Olaparib – a drug developed through UK-led and funded science – has been shown to cut the risk of cancer recurrence and improve survival rates when added to standard treatment for patients diagnosed with high-risk early-stage breast cancer who have inherited faults in their BRCA1 or BRCA2 genes.

The draft decision, which was announced by NICE, follows unsuccessful attempts to widen access to olaparib for a range of cancers linked to BRCA1 and BRCA2 gene mutations, including advanced prostate cancer and advanced breast cancer…