UK – NICE backs use of new treatment for multiple myeloma

Patients with a difficult to treat form of multiple myeloma will now gain access to a new treatment on the NHS in England and Wales, after cost regulators issued final guidance on the use of Sanofi's Sarclisa (isatuximab).

Sarclisa, administered as an intravenous infusion, plus pomalidomide and dexamethasone, is recommended for use within the Cancer Drugs Fund (CDF) as an option for treating relapsed and refractory multiple myeloma in adults.

Routine NHS funding was not approved at this stage “because the cost-effectiveness estimates are uncertain as there are limitations in the clinical data” the Institute said.

However, its green light via the CDF will allow doctors to offer the treatment as an option for people who have had lenalidomide and a proteasome inhibitor, and whose disease has progressed from their last treatment if they have had three previous forms of treatment, while more data is collated…