UK – NICE recommends Kyprolis triple combination treatment for multiple myeloma

The National Institute for Health and Care Excellence (NICE) has recommended a triple combination therapy comprised of Amgen’s Kyprolis, lenalidomide and dexamethasone for the treatment of previously-treated multiple myeloma patients.

In final guidance, NICE backed the use of Kyprolis (carfilzomib) plus lenalidomide and dexamethasone for people with multiple myeloma, who have had at least one previous therapy – including targeted therapy bortezomib (Janssen’s Velcade).

In clinical trials of the triple combination, Kyprolis with lenalidomide and dexamethasone was found to extend periods of remission and help people to live longer, compared to the current second-line treatment for multiple myeloma patients – lenalidomide and dexamethasone alone…