The Institute rejected use of the drug in this setting earlier this year on grounds that it was not cost-effective enough, but has now released draft guidelines endorsing its use, with funding via the Cancer Drugs Fund.
According to the firm, the approval marks a change in the treatment of melanoma for patients eligible for surgery, who are currently only monitored to see if their cancer returns, which is known as the “watch and wait” approach.
« There have been huge advances in the treatment of advanced melanoma in recent years, but cure rates are low. So, being able to give nivolumab to high risk patients after their surgery is a significant step forward in improving outcomes for what can be a devastating disease, » said Dr Pippa Corrie, consultant and Associate Lecturer in Medical Oncology, Cambridge University Hospitals NHS Foundation Trust.
The incidence of melanoma in the UK has has more than doubled in the last 25 years or so…