USA – FDA okays Moderna, J&J, ‘mix and match’ boosters

The US Food and Drug Administration has authorized booster doses of both the Moderna COVID-19 vaccine and the vaccine made by Janssen, the vaccines arm of Johnson & Johnson. The agency has also taken a “mix and match” approach, authorizing heterologous booster doses for all populations eligible for boosters under today’s expansion of the emergency use authorizations for COVID-19 vaccines.

A booster is recommended for all recipients of the one-dose Janssen vaccine, and recipients may choose to receive either an additional full dose of Janssen’s vaccine, a full dose of the Pfizer mRNA vaccine, or the half-strength dose of Moderna’s mRNA vaccine that was submitted for consideration as a booster.

Similarly, Moderna vaccine recipients now have the option to receive a half-strength dose of Moderna’s offering, or to receive a Janssen or Pfizer vaccine as a booster. However, the booster dose for Moderna recipients is currently authorized for individuals 65 years of age and older as well as those aged 18 through 64 who are at high risk of severe disease, or who live or work in settings putting them at risk of exposure to SARS-CoV-2. (RELATED: Unanimous thumbs up from FDA committee for Moderna booster, Regulatory Focus 14 October 2021)…