USA – New study finds brains of ‘superagers’ contain larger neurones in memory region

Brain cells of ‘superagers’ – humans aged 80 years and over who show exceptional episodic memory at least as good as individuals 20-30 years their junior – may hold the answer to resisting memory and thinking problems later in life, a Northwestern Medicine study has shown.

The study, which was published in the Journal of Neuroscience, involved the analysis of donated superager brains from the Northwestern University Alzheimer’s Disease Research Center (ADRC) Brain Bank.

The brains investigated were split into four groups: six superagers, six younger people with healthy memory and thinking skills, seven age-matched people with average memory and thinking skills, and five people with a type of mild cognitive impairment.

Compared to all other groups in the study – including younger individuals 20-30 years their junior – superagers had ‘significantly larger’ brain cells in their entorhinal cortex, an area of the brain that plays a critical role in memory and thinking abilities…