USA – US approves AZ’ hairy cell leukaemia drug

AstraZeneca and its biologics R&D arm MedImmune have bagged US approval of Lumoxiti for the treatment of hairy cell leukaemia (HCL), marking the first new treatment option in 20 years.

The decision allows physicians to prescribe the drug for patients with relapsed or refractory HCL who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog, but not for those with severe renal impairment.

HCL is a rare, chronic, and slow-growing leukaemia in which the bone marrow overproduces abnormal B cell lymphocytes. The disease can result in serious conditions such as infections, bleeding and anaemia…